Triterpenoids Isolated from <i>Ziziphus jujuba</i> Enhance Glucose Uptake Activity in Skeletal Muscle Cells
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چکیده
منابع مشابه
Exercise, GLUT4, and skeletal muscle glucose uptake.
Glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose transporter which translocates from intracellular storage depots to the plasma membrane and T-tubules upon muscle contraction. Here we discuss the current understanding of how exercise-induced muscle glucose up...
متن کاملGlucose Uptake by Rat Skeletal Muscle
Dr. Chiasson's present address is Institut de Recherches Cliniques de Montreal, Montreal, Quebec, H2W 1R7, Canada. Received for publication 5 September 1980 and in revised form 29 April 1981. 706 accumulation of hexose phosphates, which inhibit hexokinase.
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Undernutrition in rats impairs secretion of insulin but maintains glucose normotolerance, because muscle tissue presents an increased insulin-induced glucose uptake. We studied glucose transporters in gastrocnemius muscles from food-restricted and control anesthetized rats under basal and euglycemic hyperinsulinemic conditions. Muscle membranes were prepared by subcellular fractionation in sucr...
متن کاملLeukemia inhibitory factor increases glucose uptake in mouse skeletal muscle.
Members of the IL-6 family, IL-6 and ciliary neurotrophic factor (CNTF), have been shown to increase glucose uptake and fatty acid oxidation in skeletal muscle. However, the metabolic effects of another family member, leukemia inhibitory factor (LIF), are not well characterized. Effects of LIF on skeletal muscle glucose uptake and palmitate oxidation and signaling were investigated in ex vivo i...
متن کاملRegulation of exercise-stimulated glucose uptake in skeletal muscle
AMP-activated protein kinase (AMPK) is a Ser/Thr kinase that has been thought to be an important mediator for exercise-stimulated glucose uptake in skeletal muscle. Liver kinase B1 (LKB1) is an upstream kinase for AMPK and AMPK-related protein kinases, of which the function in skeletal muscle has not been well documented. Our group and others have generated mice lacking AMPK activity in skeleta...
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ژورنال
عنوان ژورنال: Journal of Nutritional Science and Vitaminology
سال: 2017
ISSN: 0301-4800,1881-7742
DOI: 10.3177/jnsv.63.193